Mark Nussbaum
Chemistry

Mark A. Nussbaum

Chairman and Professor of Chemistry, Joseph H. Moss Chair in Chemistry in Honor of Margaret Thatcher
"Higher education is about helping students become logical, clear thinkers and communicators and instilling a humble sense of wonder at the amazing universe we live in."
— Mark Nussbaum

Education

B.A., Taylor University, 1982

Ph.D., University of Illinois, 1987

Awards

Emily Daugherty Award for Teaching Excellence (Hillsdale College, 2003)

Memberships

American Chemical Society

Midwest Association of Chemistry Teachers at Liberal Arts Colleges

Sigma Xi

 

Publications

Baertschi, S. W.; Pack, B. W.; Hoaglund Hyzer, C. S.; Nussbaum, M. A. Assessing mass balance in pharmaceutical drug products: New insights into an old topic. Trends in Analytical Chemistry 2013, 49, 126-136.

Nussbaum, M. A.; Kaerner, A.; Jansen, P. J.; Baertschi, S. W. Role of “mass balance” in pharmaceutical stress testing. In Pharmaceutical Stress Testing: Predicting Drug Degradation, 2nd ed.; Baertschi, S. W., Alsante, K. M., Reed, R. A., Eds.; Drugs and the Pharmaceutical Sciences Series 210; Informa Healthcare: New York, 2011; pp. 233-253.

Houghton, D. C.; Berry, E. A.; Gilchrist, A.; Thompson, J.; Nussbaum, M. A. Biological changes along the continuum of an agricultural stream: influence of small terrestrial preserve and use of adult caddisflies in biomonitoring. J. Freshwater Ecology 2011, 26, 381-397.

 

Dumke, J. C.; Nussbaum, M. A. Adaptation of a Commercial Capillary Electrophoresis Instrument for Chemiluminescence Detection. Anal. Chem., 2007, 79, 1262-1265.

Nussbaum, M. A.; Jansen, P. J.; Baertschi, S. W. Role of “Mass Balance” in Pharmaceutical Stress Testing. In Pharmaceutical Stress Testing: Predicting Drug Degradation; Baertschi, S. W., Ed.; Drugs and the Pharmaceutical Sciences 153; Taylor & Francis; Boca Raton, FL, 2005; pp 181-204.

Allgeier, M. C.; Nussbaum, M. A.; Risley, D. S. Comparison of an Evaporative Light-Scattering Detector and a Chemiluminescent Nitrogen Detector for Analyzing Compounds Lacking a Sufficient UV Chromophore. LCGC North America, 2003, 21, 376-381.

Nussbaum, M. A.; Baertschi, S. W.; Jansen, P. J. Determination of Relative UV Response Factors for HPLC by use of a Chemiluminescent Nitrogen-Specific Detector. J. Pharm. Biomed. Anal. 2002, 27, 983-993.

 

Yang, L.; Liu, L.; Olsen, B. A.; Nussbaum, M. A. The Determination of Oxalic Acid, Oxamic Acid, and Oxamide in a Drug Substance by Ion-Exclusion Chromatography. J. Pharm. Biomed. Anal. 2000, 22, 487-493.

Nussbaum, M. A. When a Truck Becomes a Motorcycle: The Impact of Sample Load on a Chiral Capillary Electrophoresis Separation Using Mixtures of Neutral and Sulfated Cyclodextrins. Electrophoresis 1999, 20, 2664-2669.

Clodfelter, D. K.; Nussbaum, M. A.; Reilly, J. Comparison of Free Solution Capillary Electrophoresis and Size Exclusion Chromatography for Quantitating Non-Covalent Aggregation of an Acylated Peptide. J. Pharm. Biomed. Anal., 1999, 19, 763-775.

Liu, L.; Nussbaum, M. A. Systematic Screening Approach for Chiral Separations of Basic Compounds by Capillary Electrophoresis with Modified Cyclodextrins. J. Pharm. Biomed. Anal., 1999, 19, 679-694.

 

Liu, L.; Osborne, L. M.; Nussbaum, M. A. Development and Validation of a Combined Potency Assay and Enantiomeric Purity Method for a Chiral Pharmaceutical Compound Using Capillary Electrophoresis. J. Chromatogr. A, 1996, 745, 45-52.

Liu, L.; Nussbaum, M. A. Control of Enantiomer Migration Order in Capillary Electrophoresis Separations Using Sulfobutyl Ether Beta-Cyclodextrin. J. Pharm. Biomed. Anal., 1995, 14, 65-72.

Nussbaum, M. A.; Przedwiecki, J. E.; Staerk, D. U.; Lunte, S. M.; Riley, C. M. Electrochemical characteristics of Amino Acids and Peptides Derivatized with Naphthalene-2-3-dicarboxaldehyde: pH Effects and Differences in Oxidation Potentials. Anal. Chem., 1992, 64, 1259-1263.

Nussbaum, M. A.; Nekimken, H. L.; Nieman, T. A. Luminol Chemiluminescence for Determination of Iron(II) in Ferrioxalate Chemical Actinometry. Anal. Chem., 1987, 59, 211-212.

 

About

I came to Hillsdale in 2001 because I am convinced that a liberal arts education at a small, academically rigorous institution is an excellent way for a student to build a strong foundation for life as an adult and as a lifelong learner. Higher education is about helping students better understand the world around them and their place in it. It’s about helping students become logical, clear thinkers and communicators and instilling a humble sense of wonder at the amazing universe we live in.

Chemistry in particular is an excellent field for developing that sense of wonder. It helps us develop logical, critical thinking and creative visualization, and it helps students learn how to focus ideas into well-defined questions and develop ways to address those questions. Finally, chemistry encourages students to bring together information from a variety of sources in order to understand new problems.

As a teacher, I want to promote and develop these facets of my students’ thinking and also help them organize and communicate their thoughts clearly. I want my students to understand what’s going on in a reaction or an instrument, not just plug information into an equation. I want to hear that click of comprehension, that rush of “I get it now!” excitement when a topic goes from being an external assignment to an internal discovery.

Hillsdale’s chemistry department is an ideal size with seven PhD faculty and between twenty and twenty-five biochemistry and chemistry graduates per year. Students have peers to work with and befriend, but the group is small enough that faculty get to know each one personally. This department is one of the most collegial and dedicated groups of people I’ve ever had the pleasure of working with. We are academically rigorous; our students routinely perform above the national average on standardized chemistry tests; our students do well after graduation; we have outstanding facilities; and our program is approved by the American Chemical Society.

I am convinced that a liberal arts education at a small, academically rigorous institution is an excellent way for a student to build a strong foundation for life as an adult and as a lifelong learner. I believe in the mission of Hillsdale College, and I enjoy living in a small town in the northern Midwest, spending time with my family, traveling, biking, kayaking, sailing, hiking, and reading.